Clinical Manifestations

  • Chest pain
    • Severe, diffuse steady substernal pain of a crushing and squeezing nature
    • Not relieved by rest or sublingual vasodilator therapy, but requires opioids
    • May radiate to the arms (usually the left), shoulders, neck, back, and/or jaw
    • Continues for more than 15 minutes
    • May produce anxiety and fear, resulting in an increase in heart rate, BP, and respiratory rate
  • Diaphoresis, cool clammy skin, facial pallor
  • Hypertension or hypotension
  • Bradycardia or tachycardia
  • Premature ventricular and/or atrial beats
  • Palpitations, severe anxiety, dyspnea
  • Disorientation, confusion, restlessness
  • Fainting, marked weakness
  • Nausea, vomiting, hiccups
  • Atypical symptoms: epigastric or abdominal distress, dull aching or tingling sensations, shortness of breath, extreme fatigue